WebAmong the enzymes thought to process these structures, the Pif1 DNA helicase is. G-rich sequences found at multiple sites throughout all genomes may form secondary structures called G-quadruplexes (G4), which act as roadblocks for molecular motors. Among the enzymes thought to process these structures, the Pif1 DNA helicase is WebJul 1, 2008 · Function. DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G …
The Biochemical Activities of the Saccharomyces cerevisiae Pif1 ...
WebNov 26, 2024 · As Pif1 is a 5′–3′ helicase and has critical functions in DNA replication, we designed a substrate to determine whether the BaPif1 molecules bound to both arms of the fork are both active ... WebHelicases are molecular engines which translocate along nucleic acids (NA) to unwind double-strands or remodel NA-protein complexes. While they have an essential role in genome structure and expression, the rules dictating their processivity remain shortcut v2
854941 - Gene ResultPIF1 DNA helicase PIF1 [] - National Center …
WebMar 10, 2024 · Pif1p acts as a DNA helicase in mitochondria affects mtDNA replication directly and independently of the DNA helicase Rrm3p Pif1 directs long flaps toward the … WebThe evolutionarily conserved PIF1 DNA helicase family is important for the maintenance of genome stability in the yeast, Saccharomyces cerevisiae. There are two PIF1 family helicases in S. cerevisiae, Pif1p and Rrm3p that both possess 5'-->3' DNA helicase activity but maintain unique functions in telomerase regulation and semi-conservative DNA ... WebAmong the enzymes thought to process these structures, the Pif1 DNA helicase is. G-rich sequences found at multiple sites throughout all genomes may form secondary … sanford hospital sheldon ia