Nettet6. mai 2013 · Most water soluble antimicrobial polymers are linear [24 ... In the present work branched PEI functionalized with cationic groups, as well as hydrophilic and alkyl chains, PEI 25 QI 5 J 5 A8 15 , was used to determine its interaction and exchange with solid supported lipid, POPC, bilayers applying the OWLS technique. Nettet13. apr. 2016 · Linear and Branched PEIs (Polyethylenimines) and Their Property Space A chemical property space defines the adaptability of a molecule to changing conditions …
A comparison of linear and branched polyethylenimine …
Nettet29. sep. 2016 · Linear PEI is a cationic polymer commonly used for complexing DNA into nanoparticles for cell-transfection and gene-therapy applications. The … NettetBranched PEI (bPEI) and linear PEI (lPEI) can both be used effectively for gene delivery. bPEI contains a higher percentage of primary amines and is more amenable to modifications. lPEI is generally preferred for in vivo applications because of its … dr. burgess cardiology savannah
IJMS Free Full-Text Molecular Interaction of a New Antibacterial ...
NettetThe transfection efficiency of linear PEI22/DNA in vitro was generally greater than that of branched PEI/DNA when complexes were generated in salt containing buffer. However, PEI complexes generated under salt-free conditions generally had low transfection activity in vitro. In contrast, PEI22/DNA salt-free complexes were highly active in vivo. Nettet25. mar. 2024 · linear PEI coated crystal generated between 15 % and 30 % grea ter deviation than the branched PEI coating. An identical time scale has been used in b … Nettet19. mai 2024 · Hence, by considering the p K a values of branched PEI (4.5, 6.7, and 11.6 for primary, secondary, and tertiary amine groups, respectively) , it is obvious that at pH < 5, PEI exists in its fully protonated forms, and more compact NPs might be formed because of charge–charge repulsions, which may consequently enhance the … encounter times