WebThiopental is a short-acting barbiturate …. Induction agents for rapid sequence intubation in adults outside the operating room. …compromise . Reductions in ICP associated with … WebRecently, propofol, a new anaesthetic intravenous agent, the cerebrovascular effects of which seem to be similar to those of barbiturates, has also been used [4]. The aim of the …
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WebMar 31, 2024 · For children with intracranial hypertension, the primary goals during induction are to minimize severe increases in ICP and decreases in blood pressure. Most IV drugs decrease CMR o 2 and CBF, which consequently decreases ICP. 55 Historically, sodium thiopental (4–8 mg/kg) was the default induction agent for neurosurgical cases. WebIt is not known whether thiopental will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using thiopental. Thiopental can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. How is thiopental given? Thiopental is injected into a vein through an IV. mason\u0027s bearcat apbt pedigree
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WebMay 30, 2013 · In TBI, thiopental is thought to reduce ICP by decreasing cerebral blood flow and downregulating cerebral metabolic oxygen consumption [3, 6], two effects which are mediated by increased gamma-aminobutyric acid receptor conductance [3, 7]. Thiopental is highly lipophilic and therefore rapidly penetrates various tissues, such as the central ... WebOct 20, 2008 · Raised intracranial pressure (ICP) after traumatic brain injury (TBI) is common and associated with increased risk for death and disability. Despite decades of … WebNational Center for Biotechnology Information mason\u0027s birthday party